Shi'ite leader challenges Pakistan army chief over attacks


QUETTA, Pakistan (Reuters) - In a rare challenge, a Shi'ite leader publicly criticized powerful Pakistani army chief General Ashfaq Kayani over security in the country on Friday after bombings aimed at the minority sect killed 114 people.


"I ask the army chief: What have you done with these extra three years you got (in office). What did you give us except more death," Maulana Amin Shaheedi, who heads a national council of Shi'ite organizations, told a news conference.


The criticism of Kayani, arguably the most powerful man in Pakistan, highlighted Shi'ite frustrations with the state's failure to contain hard-line Sunni militant groups who have vowed to wipe out the sect.


Most of Thursday's deaths were caused by twin attacks aimed Shi'ites in the southwestern city of Quetta, near the Afghan border, where members of the minority have long accused the state of turning a blind eye to Sunni militant death squads.


Shi'ite leaders were so outraged at the latest bloodshed that they called for the military to take control of Quetta to shield them and said they would not allow the 82 victims of twin bomb attacks to be buried until their demands were met.


The burials had been scheduled to take place after Friday prayers but the bodies would remain in place until Shi'ites had received promises of protection.


Shaheedi said scores of bodies were still lying on a road. "They will not be buried until the army comes into Quetta," he said.


Violence against Pakistani Shi'ite Muslims is rising and some communities are living in a state of siege, a human rights group said on Friday.


"Last year was the bloodiest year for Shias in living memory," said Ali Dayan Hasan of Human Rights Watch. "More than 400 were killed and if yesterday's attack is any indication, it's just going to get worse."


A suicide bomber first targeted a snooker club in Quetta. A car bomb blew up nearby 10 minutes later after police and rescuers had arrived.


In all, 82 people were killed and 121 wounded. Nine police and 20 rescue workers were among the dead.


"It was like doomsday. Bodies were lying everywhere," said police officer Mir Zubair Mehmood.


The banned Sunni group Lashkar-e-Jangvi (LeJ) claimed responsibility for the attack in a predominantly Shi'ite neighborhood where the residents are ethnic Hazaras, Shi'ites who first migrated from Afghanistan in the nineteenth century.


While U.S. intelligence agencies have focused on al Qaeda and the Taliban, Pakistani intelligence officials say LeJ is emerging as a graver threat to Pakistan, a nuclear-armed, strategic U.S. ally.


It has stepped up attacks against Shi'ites across the country but has zeroed in on members of the sect who live in resource-rich Baluchistan province, of which Quetta is capital.


The paramilitary Frontier Corps is largely responsible for security in Baluchistan province but Shi'ites say it is unable or unwilling to protect them from the LeJ.


"STATE OF SIEGE"


The LeJ wants to impose a Sunni theocracy by stoking Sunni-Shi'ite violence. It bombs religious processions and shoots civilians in the type of attacks that pushed countries like Iraq close to civil war.


The latest attacks sparked an outpouring of grief, rage and fear among Shi'ites, many of whom have concluded that the state has left them at the mercy of the LeJ and other extremist groups who believe they are non-Muslims.


"The LeJ operates under one front or the other, and its activists go around openly shouting, 'infidel, infidel, Shi'ite infidel' and 'death to Shi'ites' in the streets of Quetta and outside our mosques," said Syed Dawwod Agha, a top official with the Baluchistan Shi'ite Conference.


"We have become a community of grave diggers. We are so used to death now that we always have shrouds ready."


The roughly 500,000-strong Hazara people in Quetta, who speak a Persian dialect, have distinct features and are an easy target, said Dayan of Human Rights Watch.


"They live in a state of siege. Stepping out of the ghetto means risking death," said Dayan. "Everyone has failed them - the security services, the government, the judiciary."


Earlier on Thursday, a separate bomb killed 11 people in Quetta's main market.


The United Baloch Army claimed responsibility for that blast. The group is one of several fighting for independence for Baluchistan, an arid, impoverished region with substantial gas, copper and gold reserves.


Baluchistan constitutes just less than half of Pakistan's territory and is home to about 8 million of the country's population of 180 million.


In a separate attack on Thursday, in Mingora, the largest city in the Swat valley in the northwest, at least 21 people were killed when an explosion targeted a public gathering of residents who had come to listen to a religious leader.


No one claimed responsibility for that bombing. Swat has been under army rule since a military offensive expelled Pakistani Taliban militants in 2009.


The LeJ has had historically close ties to elements in the security forces, who see the group as an ally in any potential war with neighboring India. Security forces deny any such links.


In a measure of the outrage, several Pakistani social media users posted Facebook comments urging the U.S. to expand its covert programme of drone warfare beyond Taliban strongholds on the Afghan border to target LeJ leaders in Baluchistan.


Among the dead in Quetta was Khudi Ali, a young activist who often wore a t-shirt with fake bloodstains during protests against the rising violence against Shi'ites.


Ali's Twitter profile said: "I am born to fight for human rights and peace."


(Reporting by Katharine Houreld; Editing by Jeremy Laurence)



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Skype founder browses globe for next tech earner






LONDON (Reuters) – Niklas Zennstrom, co-founder of internet phone service Skype, believes the next hot tech business will just as likely spring from Istanbul or Sao Paolo as from Silicon Valley or the coolest districts of London.


And he is prepared to fly around the world to find it.






“Talent can pop up anywhere in the world, it’s not just one city block,” the Swedish entrepreneur and venture capitalist said at the headquarters of his Atomico fund, based on upmarket New Bond Street in central London.


Zennstrom, who retains faint traces of a Swedish accent despite his years of globetrotting, is looking for start-ups ready to shift up a gear into new markets and has the experience, gained from growing Skype into a service used by millions around the world, to help them.


Skype was sold to eBay Inc in 2005 for roughly $ 3 billion, before being bought back by a consortium including Zennstrom in 2009 and then two years later sold on to Microsoft Corp for $ 8.5 billion, leaving him a multi-millionaire.


“If you have a product that works it’s important to scale (up) the business as quickly as possible,” said Zennstrom, named by Time Magazine in 2006 as one of its 100 most influential people. “As entrepreneurs, usually you may not have that experience; how does Asia work? Europe? Latin America?”


Atomico, founded by Zennstrom in 2006, has invested in companies in northern Europe including Finland-based Rovio, developer of Angry Birds, and Hailo, a London-based startup that has developed an app that connects passengers with taxi drivers and has raised $ 20 million so far.


It also led a $ 105 million funding round for U.S. online retailer Fab in July.


FUTURE PORTFOLIO


The investment fund, whose London office reception is decked out with simple designer furniture and modern art pieces, has opened offices in Turkey and Brazil, emerging markets with growing middle classes eager to shop online and buy internet services.


Zennstrom wants to make these markets a large part of Atomico’s portfolio in future.


The firm in 2011 backed Brazilian online retailers such as car parts supplier Connect Parts and announced a $ 16 million investment in a Russian online travel agency in October.


Atomico is not necessarily looking for the latest gizmo or internet trend, but savvy businesses with talented leaders who can take advantage of growth in nascent sectors such as e-commerce.


And Zennstrom, softly spoken and wearing an open-necked shirt and dark jacket, believes emerging market growth is fuelling a new breed of optimism and ambition.


“It’s a much more of an entrepreneurial spirit (in Turkey and Brazil) compared to southern European where it’s a depressed mindset,” he said.


Zennstrom earned his stripes in the tech world after helping launch file-sharing service Kazaa more than a decade ago, which failed as a business but paved the way for Skype.


He said getting investment today was far easier than when he was starting Skype. It took him a year to secure funding, whereas today the most talented entrepreneurs with the best ideas could take their pick of investors.


There is also increasing recognition that entrepreneurs might want to realize some of the value of their creations, something he said was lacking when Skype became successful.


“There was really no IPO market and it was not really accepted for founders to sell some of their shares to get some money off the table,” he said, adding that before Skype was sold to eBay, he could not even secure a mortgage on an apartment.


“I think we made the right decision for the time in terms of selling (Skype),” he said. “Today as an entrepreneur you have more options.”


(Editing by David Holmes)


Internet News Headlines – Yahoo! News





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Kate's Official Portrait Unveiled









01/11/2013 at 08:40 AM EST







From left: artist Paul Emsley, the Duchess and Duke of Cambridge


REX USA


The Duke and Duchess of Cambridge had an art outing early Friday – for the unveiling of her official portrait.

And they were not alone. Kate's parents and siblings also made the breakfast trip to the National Portrait Gallery – the Duchess's first official outing since she handed out awards at a sports honors evening in December.

Her reaction to her portrait? "I thought it was brilliant," Kate, who showed no sign of a baby bump in her burgundy Whistles dress, said at the reception.

She also thanked artist Paul Emsley, a Glasgow-born, South African-raised painter, while William pronounced the canvas – which happens to be located in the same gallery as a rendering of a naked David Beckham (it will soon be moved elsewhere) – "absolutely beautiful"

Kate sat for Emsley in two sittings last May and June, both at his studio in Bradford-upon-Avon, southwest England, and at Kensington Palace. Working from photographs he took, he spent 3½ months to create the painting.

Kate's Official Portrait Unveiled| The British Royals, Kate Middleton, Prince William

Official portrait of Kate, Duchess of Cambridge, by artist Paul Emsley

Sang Tan / AP

He says Kate wanted "to convey her natural self as opposed to her official self. I was always aware of the fact that we would use the hair very much as a kind of a frame for the face, and not too much jewelry apart from the earring, to try to create something of her natural warmth, her natural serenity without too much busyness in the portrait."

He told PEOPLE, "If you are working with someone who has whose face is just a lovely face, it's harder to find something in the portrait that gives it some sort of gravitas. In this case I've tried to do that with the smile and the dimples and the shadows around the face."

Director of the National Portrait Gallery Sandy Nairne, called the painting "very direct, simple. Modern contemporary portrait." As for the subject, "She was really positive about it," and, as he told PEOPLE, "She seemed very well, terrific."

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Flu season strikes early and, in some places, hard


NEW YORK (AP) — From the Rocky Mountains to New England, hospitals are swamped with people with flu symptoms. Some medical centers are turning away visitors or making them wear face masks, and one Pennsylvania hospital set up a tent outside its ER to deal with the feverish patients.


Flu season in the U.S. has struck early and, in many places, hard.


While flu normally doesn't blanket the country until late January or February, it is already widespread in more than 40 states, with about 30 of them reporting some major hot spots. On Thursday, health officials blamed the flu for the deaths of 20 children so far.


Whether this will be considered a bad season by the time it has run its course in the spring remains to be seen.


"Those of us with gray hair have seen worse," said Dr. William Schaffner, a flu expert at Vanderbilt University in Nashville.


The evidence so far points to a moderate season, Schaffner and others say. It looks bad in part because last year was unusually mild and because the main strain of influenza circulating this year tends to make people sicker and really lay them low.


David Smythe of New York City saw it happen to his 50-year-old girlfriend, who has been knocked out for about two weeks. "She's been in bed. She can't even get up," he said.


Also, the flu's early arrival coincided with spikes in a variety of other viruses, including a childhood malady that mimics flu and a new norovirus that causes vomiting and diarrhea, or what is commonly known as "stomach flu." So what people are calling the flu may, in fact, be something else.


"There may be more of an overlap than we normally see," said Dr. Joseph Bresee, who tracks the flu for the Centers for Disease Control and Prevention.


Most people don't undergo lab tests to confirm flu, and the symptoms are so similar that it can be hard to distinguish flu from other viruses, or even a cold. Over the holidays, 250 people were sickened at a Mormon missionary training center in Utah, but the culprit turned out to be a norovirus, not the flu.


Flu is a major contributor, though, to what's going on.


"I'd say 75 percent," said Dr. Dan Surdam, head of the emergency department at Cheyenne Regional Medical Center, Wyoming's largest hospital. The 17-bed emergency room saw its busiest day ever last week, with 166 visitors.


The early onslaught has resulted in a spike in hospitalizations. To deal with the influx and protect other patients from getting sick, hospitals are restricting visits from children, requiring family members to wear masks and banning anyone with flu symptoms from maternity wards.


One hospital in Allentown, Pa., set up a tent this week for a steady stream of patients with flu symptoms. But so far "what we're seeing is a typical flu season," said Terry Burger, director of infection control and prevention for the hospital, Lehigh Valley Hospital-Cedar Crest.


On Wednesday, Boston declared a public health emergency, with the city's hospitals counting about 1,500 emergency room visits since December by people with flu-like symptoms.


All the flu activity has led some to question whether this year's flu shot is working. While health officials are still analyzing the vaccine, early indications are that it's about 60 percent effective, which is in line with what's been seen in other years.


The vaccine is reformulated each year, based on experts' best guess of which strains of the virus will predominate. This year's vaccine is well-matched to what's going around. The government estimates that between a third and half of Americans have gotten the vaccine.


In New York City, 57-year-old Judith Quinones skipped getting a flu shot this season and suffered her worst case of flu-like illness in years. She was laid up for nearly a month with fever and body aches. "I just couldn't function," she said.


But her daughter got the vaccine. "And she got sick twice," Quinones said.


Europe is also suffering an early flu season, though a milder strain predominates there. Flu reports are up, too, in China, Japan, the West Bank, the Gaza Strip, Algeria and the Republic of Congo. Britain has seen a surge in cases of norovirus.


On average, about 24,000 Americans die each flu season, according to the CDC. That's an estimate — the agency does not keep a running tally of adult flu deaths each year, only for children. Some state health departments do keep count, and they've reported dozens of flu deaths so far.


Flu usually peaks in midwinter. Symptoms can include fever, cough, runny nose, head and body aches and fatigue. Some people also suffer vomiting and diarrhea, and some develop pneumonia or other severe complications.


Most people with flu have a mild illness and can help themselves and protect others by staying home and resting. But people with severe symptoms should see a doctor. They may be given antiviral drugs or other medications to ease symptoms.


Flu vaccinations are recommended for everyone 6 months or older. Of the 20 children killed by the flu this season, only two were fully vaccinated.


___


AP Medical Writer Maria Cheng in London contributed to this report.


___


Online:


CDC flu: http://www.cdc.gov/flu/index.htm


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Stock futures little changed after S&P hit five-year high


NEW YORK (Reuters) - Stock index futures were little changed on Friday, a day after the S&P 500 hit a five-year high and following higher-than-expected results from Wells Fargo.


Wells Fargo , the first major U.S. bank to post earnings this season, reported a higher fourth-quarter profit on Friday as it set aside less money to cover bad loans and made more fees from mortgages. Still, its shares fell 1.1 percent to $35 in premarket trading.


Basic materials shares could be hurt after China's annual consumer inflation rate picked up to a seven-month high, narrowing the scope for the central bank to boost the economy by easing monetary policy.


"The bigger news lies ahead of us in terms of earnings and also reports on Christmas sales, which seem to be poor so far," said Rick Meckler, president of investment firm LibertyView Capital Management in Jersey City, New Jersey.


Best Buy shares were volatile in premarket trading after it reported flat holiday sales at established U.S. stores. Shares were last up 4.8 percent at $12.80.


Meckler said that in the absence of major news, the market will continue to absorb some of the money that comes in from institutional investors at the start of the year, which could give equities an upside bias.


S&P 500 futures dipped 1 point and were slightly below fair value, a formula that evaluates pricing by taking into account interest rates, dividends and time to expiration on the contract. Dow Jones industrial average futures fell 7 points, and Nasdaq 100 futures lost 1 point.


American Express said it would take a $600-million quarterly charge relating to 5,400 job cuts and payment of legal bills, a move likely to halve its net income. Its shares dipped 0.5 percent in premarket trading to $60.51.


Boeing's 787 Dreamliner jet was dogged by further incidents that tested confidence in the new plane. It suffered a cracked cockpit window and an oil leak on separate flights in Japan on Friday. The US Department of Transportation said the jet would be subject to a review of its critical systems by regulators. Boeing shares fell 1.5 percent to $75.90 in premarket trading.


In a move that could support US equities and boost the global economic outlook, the Japanese government approved a massive $117 billion of spending to revive the world's third-largest economy in the biggest stimulus plan since the financial crisis.


(Editing by Bernadette Baum)



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NATO official says more missiles launched in Syria


BRUSSELS (Reuters) - A short-range ballistic missile was fired inside Syria on Wednesday, following similar launches last week, a NATO official said on Thursday.


The official condemned as "reckless" the missile launches, which U.S. officials called an escalation of the 21-month-old Syrian civil war when their use was first spotted last month.


"The use of such indiscriminate weapons shows utter disregard for the lives of the Syrian people," he said.


The official said NATO had detected the launch of an unguided, short-range ballistic missile inside Syria on Wednesday, following similar launches on January 2 and 3. All the missiles were fired from inside Syria and landed in northern Syria, he said.


The description of the missiles fits the Scuds that are in the Syrian military's armory, but the official said NATO could not confirm the type of missile used.


The NATO official was responding to a report from a Syrian opposition activist living near the Qaldoun army base, 50 km (30 miles) north of Damascus, who said four large rockets, apparently Scuds, were fired from the base overnight.


NATO has agreed to send Patriot anti-missile batteries to protect its member Turkey from possible missile attack from Syria.


(Reporting by Adrian Croft; editing by Rex Merrifield and Sebastian Moffett)



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Netflix announces ‘Super HD’ and 3D streaming for select ISPs






Netflix (NFLX) on Tuesday announced new enhanced streaming options for users on select ISPs. Following a series of rumors that suggested as much, Netflix has confirmed the availability of “Super HD” streaming — which is simply Netflix’s branding for 1080p content — and 3D video streaming. Both services are available immediately with a huge caveat: only Netflix subscribers with Cablevision or Google Fiber Internet service have access to the new content. For those lucky subscribers, Super HD and 3D content is accessible using a number of devices including the Wii U, compatible Roku players, the Apple TV, Windows 8 PCs and select smart TVs and Blu-ray players. Netflix’s full press release follows below.



Netflix “Open Connect” Delivery Network Gains Widespread Global Acceptance
Cablevision Most Recent Major Provider to Join Open Connect
New Super HD and 3D Video Formats Available on Open Connect






[More from BGR: Apple’s next iPhone to reportedly feature larger screen and ‘brand new exterior design’]


Jan 8, 2013


LAS VEGAS, Jan. 8, 2013 /PRNewswire/ — Netflix Open Connect, the single purpose video content delivery network launched last year, is now delivering the majority of Netflix international traffic and is growing at a rapid pace in the domestic market.


In early 2012 Netflix began enabling Internet service providers (ISPs) to receive, at no cost to them, Netflix video directly at the interconnection point of the ISP’s choice. By connecting directly through Open Connect, ISPs can more effectively manage their networks and more efficiently deliver Internet services to consumers, including the more than 1 billion hours of Netflix TV shows and movies consumers watch every month.


Netflix Open Connect is now widely deployed around the world, serving the vast majority of Netflix video in Europe, Canada and Latin America, and a growing proportion in the U.S., where Netflix has over 25 million streaming members.


“Leading-edge ISPs around the world such as Cablevision, Virgin Media, British Telecom, Telmex, Telus, TDC, GVT, among many others, are already participating in Open Connect to provide the highest-possible quality Netflix service to consumers,” said Netflix Chief Executive Officer Reed Hastings. “Our goal is to have all of our members served by Open Connect as soon as possible.”


“Optimum is committed to providing the highest-quality TV, phone and Internet to our customers, and our new partnership with Netflix supports this critical objective,” said James L. Dolan, president and CEO of Cablevision, the most recent major provider to join Open Connect. “With Open Connect, we are establishing a direct local connection with Netflix that delivers a higher-quality Netflix viewing experience for Optimum customers than Verizon or AT&T can provide, including access to new Netflix Super HD and 3D TV shows and movies.”


Netflix Super HD and 3D


Now available through Open Connect partners, Netflix Super HD is the highest quality video format offered by Netflix, providing an even better picture on 1080p HDTVs.


In the U.S., Netflix is also for the first time offering a small number of titles streaming in 3D through Open Connect partners. Available for 3D viewing are, among other titles, the action fantasy drama “Immortals,” Red Bull Media House’s snowboarding documentary “The Art of Flight,” and a number of titles from the Discovery/Sony/Imax joint venture 3net Studios – including the native, original 3D series “African Wild,” “Scary Tales,” and “Live Fire.” Depending on member demand, Netflix will consider adding 3D titles and expanding availability to international markets.


“These new Super HD and 3D formats are more challenging to deliver than our other video streams, which is why we will deliver them through Open Connect,” said Ken Florance, vice president of content delivery at Netflix. “Any ISP that wants to be able to deliver our new formats can do so easily and for free.”


Netflix members can verify if their ISP is part of Open Connect and provides access to Netflix Super HD and, in the U.S. only, 3D on this Web site: http://www.netflix.com/superhd


ISPs that are not yet on Open Connect can contact Netflix at openconnect.netflix.com to start their Open Connect relationship. As part of Open Connect, Netflix is also sharing its hardware design and the open source software components. These designs are suitable for any other provider of large media files and are very cost efficient.



Linux/Open Source News Headlines – Yahoo! News





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It's a Girl for Lily Allen




Celebrity Baby Blog





01/10/2013 at 08:30 AM ET



Lily Allen Welcomes Baby
PA Photos/Landov


Cue the lullabies: Lily Allen is a mom — again!


The “Smile” singer and her husband Sam Cooper welcomed her second daughter — and the baby girl shares her special day with rock legends Elvis and David Bowie. Marnie Rose arrived on Jan. 8, according to reports.


The couple — who wed in Gloucestershire, England in June 2011 — are already parents to 1-year-old daughter Ethel Mary.


Her rep declined to confirm the pregnancy in July, but after stepping out several times with a burgeoning belly, no official confirmation was needed when 27-year-old Allen appeared radiant on the red carpet during the British Fashion Awards in November.


On New Year’s Eve, Allen was anxious the tot would emerge soon, Tweeting she was “only planning on spending a few days of [2013] pregnant. Unlike the last 3 years.” And she said she had been sampling curries to try to force labor.


A rep for the singer (who goes by her married name Cooper) didn’t immediately respond to requests for comment or statement, but Allen appeared to acknowledge the news Thursday when she thanked fans, writing, “Quite overwhelmed by all the well wishing going on. THANKYOU everybody x x x”


One of those came from actor friend Charlie Condou, who Tweeted he had a “little cry” when Lily “told me Marnie Rose was born” on his birthday.


– Anya Leon and Simon Perry


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Retooling Pap test to spot more kinds of cancer


WASHINGTON (AP) — For years, doctors have lamented that there's no Pap test for deadly ovarian cancer. Wednesday, scientists reported encouraging signs that one day, there might be.


Researchers are trying to retool the Pap, a test for cervical cancer that millions of women get, so that it could spot early signs of other gynecologic cancers, too.


How? It turns out that cells can flake off of tumors in the ovaries or the lining of the uterus, and float down to rest in the cervix, where Pap tests are performed. These cells are too rare to recognize under the microscope. But researchers from Johns Hopkins University used some sophisticated DNA testing on the Pap samples to uncover the evidence — gene mutations that show cancer is present.


In a pilot study, they analyzed Pap smears from 46 women who already were diagnosed with either ovarian or endometrial cancer. The new technique found all the endometrial cancers and 41 percent of the ovarian tumors, the team reported Wednesday in the journal Science Translational Medicine.


This is very early-stage research, and women shouldn't expect any change in their routine Paps. It will take years of additional testing to prove if the so-called PapGene technique really could work as a screening tool, used to spot cancer in women who thought they were healthy.


"Now the hard work begins," said Hopkins oncologist Dr. Luis Diaz, whose team is collecting hundreds of additional Pap samples for more study and is exploring ways to enhance the detection of ovarian cancer.


But if it ultimately pans out, "the neat part about this is, the patient won't feel anything different," and the Pap wouldn't be performed differently, Diaz added. The extra work would come in a lab.


The gene-based technique marks a new approach toward cancer screening, and specialists are watching closely.


"This is very encouraging, and it shows great potential," said American Cancer Society genetics expert Michael Melner.


"We are a long way from being able to see any impact on our patients," cautioned Dr. Shannon Westin of the University of Texas MD Anderson Cancer Center. She reviewed the research in an accompanying editorial, and said the ovarian cancer detection would need improvement if the test is to work.


But she noted that ovarian cancer has poor survival rates because it's rarely caught early. "If this screening test could identify ovarian cancer at an early stage, there would be a profound impact on patient outcomes and mortality," Westin said.


More than 22,000 U.S. women are diagnosed with ovarian cancer each year, and more than 15,000 die. Symptoms such as pain and bloating seldom are obvious until the cancer is more advanced, and numerous attempts at screening tests have failed.


Endometrial cancer affects about 47,000 women a year, and kills about 8,000. There is no screening test for it either, but most women are diagnosed early because of postmenopausal bleeding.


The Hopkins research piggybacks on one of the most successful cancer screening tools, the Pap, and a newer technology used along with it. With a standard Pap, a little brush scrapes off cells from the cervix, which are stored in a vial to examine for signs of cervical cancer. Today, many women's Paps undergo an additional DNA-based test to see if they harbor the HPV virus, which can spur cervical cancer.


So the Hopkins team, funded largely by cancer advocacy groups, decided to look for DNA evidence of other gynecologic tumors. It developed a method to rapidly screen the Pap samples for those mutations using standard genetics equipment that Diaz said wouldn't add much to the cost of a Pap-plus-HPV test. He said the technique could detect both early-stage and more advanced tumors. Importantly, tests of Paps from 14 healthy women turned up no false alarms.


The endometrial cancers may have been easier to find because cells from those tumors don't have as far to travel as ovarian cancer cells, Diaz said. Researchers will study whether inserting the Pap brush deeper, testing during different times of the menstrual cycle, or other factors might improve detection of ovarian cancer.


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Exhausted Egyptians count cost of political turmoil


ZAGAZIG, Egypt (Reuters) - These days, craftsmen, shopkeepers and other inhabitants of the Egyptian Delta town of Zagazig are often too busy making ends meet to ponder why life seems to be getting harder every day.


But when, exhausted, they finally come home and sit down to their evening meal, conversations inevitably turn to growing hardship and the frightening prospect of cuts in food subsidies as the economy slides further into crisis.


With their patience already stretched after years of upheaval, Egyptians - from the capital Cairo to smaller towns like Zagazig - appear to be nearing the point where discontent could explode into a new wave of unrest.


"There is no security. There is nothing," said Soheir Abdel Moneim, a retired school teacher, as she hurried through an open-air market in Zagazig in search of vegetables she could afford.


"The pound is falling. Everything is more expensive. Is there anything that has not become more expensive?" she asked with a shrug, as traders on bicycles loaded with their wares dodged through the chaos of the market.


Nearby, a torn poster of President Mohamed Mursi beams from the wall of a crumbling brick house, with the words "Liars! Liars!" scrawled over his face.


The mood of growing nervousness is bad news for Mursi, who faces a parliamentary election in coming months, and a new round of political feuding that could pitch Egypt back into civil strife.


Egypt's economy, once strong and popular among investors, has been in tatters since the revolt of 2011 that ousted Hosni Mubarak and shook the country to its foundations.


Disagreements over a new national constitution late last year triggered violent protests, dealing another blow to the economy and eroding trust in Mursi's government.


A country where cuts in food subsidies have caused riots in the past now faces the risk of further upheaval as Mursi prepares to impose austerity measures in order to obtain a desperately needed $4.8 billion loan from the International Monetary Fund.


In Zagazig, people worry about the future.


Farouk Sarhan, the 74-year-old manager of a shop selling women's clothes, said sales were already down by almost 50 percent from just a few weeks ago.


"No one is selling or buying. I had more activity last year," he said, stubbing out a cigarette with a deep sigh in his tiny store lined with mannequins of veiled women.


"Customers are not buying as much as before because of the economic situation."


The price of fresh food often goes up in winter but shoppers in the Zagazig market said recent increases had been steep, with tomatoes and cauliflower about 50 percent dearer than at the start of the year.


WHAT NEXT?


Egypt has been on the ropes since investors and tourists fled after the revolt, when people rose up to demand their freedom and also an end to economic policies they said simply lined the pockets of the rich.


On the economic front, the picture remains grim, although Qatar's decision to lend Egypt another $2 billion has offered some respite.


Foreign reserves are dwindling and the pound has been hitting new lows daily. Food and raw materials from abroad have become more expensive, hurting businesses and families in a desert nation which relies on imports to feed itself.


As in other parts of Egypt, people in Zagazig see complex economic trends in terms of the daily hardships they must endure, and it is Mursi's government and his Muslim Brotherhood allies who get the blame.


"Mursi doesn't feel our grievances," said Emad, a man in his late 30s who sells traditional Egyptian clothes by the side of a dusty street. He said he had been forced to raise prices to cover rising costs, upsetting his customers.


Pointing to one of the black embroidered gowns, Emad said: "We used to sell this for 35 pounds ($5.40). Now it's 45 pounds. We didn't raise the prices. Traders did.


"Very few people are buying. I used to sell 50 pieces a day, and now I sell 15 or 20. Today I still haven't sold anything."


Reliable opinion polls are unavailable in Egypt and it is hard to gauge how widespread people's views are. But in Zagazig, most of those interviewed by Reuters echoed Emad's feelings.


Economists worry that continued turmoil could prompt people and businesses to convert their savings into dollars en masse - a risky process known as dollarisation which has caused trouble in many emerging market crises before.


But in Zagazig, people laughed at the idea, saying only the rich could afford to buy foreign currency. "Dollars?" asked Nabil, a local trader, as others burst into laughter. "Give me some dollars! Of course we don't have any!"


SUPPORT FOR MURSI


But some were prepared to give Mursi a chance.


In the nearby village of al-Adwa, where the future president grew up in the family of a local farmer, brick walls and fences were plastered with posters of Mursi.


A crowd of farmers standing by the side of a dirt track cutting through the village shook their fists and shouted "Mursi! Mursi!" when asked about their political views.


But even in Adwa, where Mursi appeared to enjoy rock-solid support, locals said sudden increase in taxes or abrupt cuts to fuel or food subsidies would cost him dearly.


"If that happens that would be the worst thing. What am I going to do as a farmer?" said Said Youssef, his hands black from working the land. "Where are we going to get the money?"


Another man, Aly Saber, 65, said fertilizer prices had gone up by 50 Egyptian pounds in the past year alone, making his business less profitable.


"Things are tough here in the rural areas," he said as others nodded in agreement. "Everything is becoming more expensive."


Mohamed Gamal, the 42-year-old owner of a tiny shop selling kitchen appliances, said business was so bad that he would sometimes go for days without a single customer.


"I import goods all the time. Prices have gone up by 10-40 percent since the revolution. It's gone up even more in recent weeks," said Gamal, who, Like Mursi, grew up in Adwa.


He said his neighbors were suspicious about why he had to keep raising his prices.


"People just don't believe me," he said, hunched over his desk, cigarette smoke swirling above stacks of unsold trays, cups and ironing boards. "They are not convinced why things are getting more expensive. I buy them, and they stack up."


($1 = 6.4809 Egyptian pounds)


(Writing by Maria Golovnina; Editing by Giles Elgood)



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